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UAE has 15 GLP-1 studies on record but only 1 is recruiting or active now

UAE has 15 GLP-1 studies on record but only 1 is recruiting or active now

Five peptides with no US approval on record have 29 registered studies worldwide combined. Semaglutide alone has 788.

Zavis Data Science DeskData & Analytics
19 Oct 20266 min read
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Key findings

  • UAE: 15 GLP-1 studies on record, 1 recruiting or active now
  • GCC: 35 studies on record, 10 recruiting or active
  • US FDA approved 8 GLP-1 submissions in 90 days, 0 original generics
  • 9 liraglutide presentations listed as current US shortages
  • 29 registered studies combined for five peptides with no US approval on record

Only 1 of the 15 registered studies of GLP-1 and related medicines with a site in the UAE is recruiting or active now, according to the Zavis GLP-1 and Peptides Monitor. The monitor read public study registries on 19 October 2026. Across the six GCC countries there are 35 such studies on record. Of these, 10 are recruiting or active and 7 are recruiting.

These numbers matter to hospitals and clinics that want to host research. They also matter to insurers estimating future demand for these medicines and to patients who want to know whether local studies are open. Saudi Arabia has 5 studies recruiting or active and Kuwait has 4. The UAE's single active study is a Phase 3 study of orforglipron sponsored by Eli Lilly and Company. That study also has a site in Saudi Arabia.

The Gulf study pipeline

Zavis analysis of ClinicalTrials.gov, the US National Library of Medicine's public study registry, shows 15 studies of GLP-1 and related medicines with a UAE site and 15 with a site in Saudi Arabia. Kuwait has 8 and Qatar has 2. The registry shows no such studies with a site in Bahrain or Oman.

Semaglutide accounts for the most GCC studies, with 12 on record and 2 recruiting or active. Liraglutide follows with 9 and tirzepatide with 5. Survodutide has 3 GCC studies, 2 of them recruiting or active. Both of those are Phase 3 studies sponsored by Boehringer Ingelheim with sites in Saudi Arabia. In Kuwait, Dasman Diabetes Institute is the lead sponsor of several recruiting studies, including studies of tirzepatide. In Qatar, a liraglutide study sponsored by Weill Cornell Medical College in Qatar is listed as active but not recruiting.

GLP-1 and related studies recruiting or active at GCC sites
Registry IDMedicinesLead sponsorPhaseStatusGCC countries
NCT07613307orforglipronEli Lilly and CompanyPhase 3RecruitingUnited Arab Emirates, Saudi Arabia
NCT07614412semaglutideMinistry of Health, Saudi ArabiaPhase 2Not yet recruitingSaudi Arabia
NCT07574723tirzepatideDasman Diabetes InstituteNot applicableRecruitingKuwait
NCT07096908tirzepatideDasman Diabetes InstitutePhase 4RecruitingKuwait
NCT06885736Class named, no medicineDasman Diabetes InstituteNot applicableRecruitingKuwait
NCT06632444survodutideBoehringer IngelheimPhase 3RecruitingSaudi Arabia
NCT06632457survodutideBoehringer IngelheimPhase 3RecruitingSaudi Arabia
NCT06571383semaglutideNovo Nordisk A/SPhase 4Active not recruitingSaudi Arabia
NCT06374875Class named, no medicineThe Cleveland ClinicPhase 4RecruitingKuwait
NCT02879409liraglutideWeill Cornell Medical College in QatarNot applicableActive not recruitingQatar

What the US and EU approved or changed

In the 90 days to 19 October, the US Food and Drug Administration approved 8 submissions for GLP-1 medicines, according to Zavis analysis of openFDA records. The count covers both original applications and supplements. Of these, 3 were efficacy supplements, which cover new or changed uses. They went to 2 medicines, Mounjaro and Zepbound, both tirzepatide, and were approved on 27 and 26 August 2026. The other approvals in the period were labelling supplements for synthetic exenatide, Ozempic and Foundayo (orforglipron). The FDA approved no original generic GLP-1 applications in the period.

US FDA approvals for GLP-1 medicines in the last 90 days
DateMedicineApplicationApprovalCategorySubmissions
2 October 2026Exenatide synthetic (exenatide)ANDA206697SupplementLabeling3
27 August 2026Ozempic (semaglutide)NDA209637SupplementLabeling1
27 August 2026Mounjaro (tirzepatide)NDA215866SupplementEfficacy2
26 August 2026Zepbound (tirzepatide)NDA217806SupplementEfficacy1
4 August 2026Foundayo (orforglipron)NDA220934SupplementLabeling1

In the European Union, 13 GLP-1 and related medicines are authorised through the centralised procedure, according to the European Medicines Agency's medicines data. Of these, 4 were first authorised in the last 12 months. They are Kyinsu (insulin icodec and semaglutide) on 24 November 2025, Kayshild (semaglutide) on 26 March 2026, and Ablymico and Liraglutide STADA, both liraglutide, on 15 July 2026. One more medicine, Foundayo, has a committee opinion and is awaiting a marketing authorisation decision. Lyxumia and Bydureon are listed as withdrawn.

The FDA drug shortage list also has GLP-1 entries. It lists 9 GLP-1 presentations as current shortages, and every one is a liraglutide injection, including Victoza and Saxenda presentations. Another 5 presentations are listed as to be discontinued, including Rybelsus tablets. These entries cover the US market. They do not describe supply in the UAE or the wider GCC.

Five peptides, 29 registered studies

ClinicalTrials.gov holds 29 registered studies worldwide for five peptides with no US approval on record: thymosin beta-4 (TB-500), BPC-157, ipamorelin, GHK-Cu and CJC-1295. That count is for all five combined. Semaglutide alone has 788 registered studies, with 109 of them showing posted results. Tirzepatide has 303 registered studies, with 47 showing posted results.

Among the five, thymosin beta-4 (TB-500) has the most registered studies, 18, and 8 of them show posted results. BPC-157 has 4 registered studies, ipamorelin 3, GHK-Cu 3 and CJC-1295 1. None of these four shows any posted results. Two other peptides in the table, tesamorelin and sermorelin, have a US approval on record. They have 24 and 27 registered studies respectively.

Registered studies on ClinicalTrials.gov: GLP-1 medicines and other peptides
SubstanceRegistered studies worldwideWith results postedUS approval on record (Drugs@FDA)
Semaglutide788109Yes
Tirzepatide30347Yes
Tesamorelin2410Yes
Sermorelin2711Yes
Thymosin beta-4 (TB-500)188No
BPC-15740No
Ipamorelin30No
GHK-Cu (copper peptide)30No
CJC-129510No

A registered study shows that research is taking place. It is not evidence that a substance works or is safe. Counts are matched by name, and some studies may include a substance only as a comparator. Peptides can also be sold under names that differ from the registered ones, and the counts cover only the names shown.

Obesity rates for context

World Health Organization estimates for 2024 put adult obesity at 42% in Qatar, the highest of the six GCC countries. Kuwait follows at 40.4% and Saudi Arabia at 40.1%. The UAE ranks fifth of the six at 31.6%, ahead of Oman at 30.5%. The figures are age-standardised.

Adults with obesity in the GCC (WHO, age-standardised)
CountryAdults with obesity (%)Year
Qatar422024
Kuwait40.42024
Saudi Arabia40.12024
Bahrain34.92024
United Arab Emirates31.62024
Oman30.52024

What it means

Operators: The UAE has as many GLP-1 studies on record as Saudi Arabia but far fewer open now. Hospitals that want to host research can check the public registry for studies that are recruiting at Gulf sites.

Insurers: New EU authorisations and US efficacy supplements change the formal record of approved products and uses. Benefit reviews may need to follow that record as it changes.

Patients: Before joining a study, check its registry entry for its status and its sites. Decisions about any medicine or peptide belong with a licensed doctor.

Sources

ZD

Zavis Data Science Desk

Data & Analytics

The Zavis Data Science Desk publishes the monthly Zavis indices at zavis.ai/intelligence/data. They are bui...

Source: Zavis Intelligence Desk