G6PD deficiency in a newborn

Newborn red blood cells already change quickly after birth. With G6PD deficiency, extra breakdown can raise bilirubin and lead to jaundice or anaemia. A newborn may look well at first, so clinicians may recommend observation, a bilirubin check, or a [Blood Test](/treatments/diagnostics-and-screening/blood-test/) when family history or symptoms suggest risk.

G6PD deficiency is inherited and is linked to the X chromosome. It is not caused by anything a parent did during pregnancy. The child’s care team can explain the family pattern and record the diagnosis for future appointments.

Follow the newborn team’s plan for feeding and follow-up. Tell the doctor or pharmacist about the diagnosis before your baby receives a medicine, supplement or traditional remedy. Watch the baby’s colour in natural light, keep feeding records if advised, and attend repeat checks. Do not stop prescribed treatment without speaking with the clinician.

Contact the maternity or paediatric team promptly if yellowing becomes deeper or spreads, feeding drops, the baby is unusually sleepy, has fewer wet nappies, feels floppy, or develops [Pale Skin](/symptoms/pale-skin/). Go for urgent assessment if the baby is difficult to wake, has breathing difficulty, or becomes blue or very weak. [Dark Urine](/symptoms/dark-urine/) should also be reported.

Ask how the diagnosis was made, which warning signs matter at home, when bilirubin or blood checks are due, and which medicines or remedies your baby must avoid.