What should you know about filler dissolve hyaluronidase?

Hyaluronidase is an enzyme used by a clinician to disperse or reduce hyaluronic acid filler. It may be considered when filler has caused an unwanted lump, asymmetry, overcorrection, or a suspected circulation problem. It does not dissolve every filler type, so identifying the product and treatment area matters.

The enzyme may also affect naturally occurring hyaluronic acid near the injection site, and the treated area can become temporarily swollen, red, tender, or bruised. The visible change is not always immediate, and more than one clinical review may be needed.

Contact the original injector or another qualified medical professional experienced with filler complications. Share the product name, treatment date, injection locations, medicines, allergies, and photographs showing how the area changed. Do not attempt to press, puncture, or self-treat a filler lump.

Ask whether the concern is a cosmetic adjustment, inflammation, infection, or a possible vascular problem, because each requires a different response. Learn about [Hyaluronidase](/materials/hyaluronidase/) and the wider context of [Dermal Fillers](/treatments/injectables/dermal-fillers/).

Seek urgent medical assessment for severe or escalating pain, pale or dusky skin, unusual mottling, a cool area, blistering, or sudden vision change after filler. Facial weakness, trouble speaking, or a severe headache also require emergency attention. Do not wait for a routine appointment when these symptoms appear.

Was my original filler made from hyaluronic acid? What finding are you treating, and how will you monitor it? Could the enzyme affect nearby tissue? What should I expect after treatment, and which changes require urgent contact?