What should you know about regression structures dermoscopy?

A dermatoscope magnifies a lesion and helps reveal colours and surface patterns that are difficult to see with the naked eye. Regression describes an area where pigment appears to have faded or been replaced by changes resembling a small scar. A clinician may describe white scar-like zones, grey dots, or blue-grey granularity as regression structures.

These findings are clues, not a diagnosis. They can occur in melanoma, but similar appearances may also be seen in benign moles or previously inflamed skin. Their significance depends on the lesion's overall symmetry, colours, borders, evolution, and whether the pattern is organised. A photograph or earlier dermoscopic image can help show whether the area is stable or newly developing.

Ask the examining clinician what the regression pattern looks like and how it fits with the rest of the lesion. They may recommend monitoring with a baseline image when the appearance is not clearly concerning, or removal and laboratory examination when the pattern, history, or change warrants tissue assessment. Do not scratch, pick, or attempt to remove the spot yourself.

Keep a simple record of changes in size, shape, colour, bleeding, crusting, or sensation. Use the same lighting for personal photographs, but do not use a phone image as a substitute for an examination with a [Dermatoscope](/technology/dermatoscope/).

Arrange a timely skin assessment if a mole or pigmented mark is changing, develops several distinct colours, becomes asymmetrical, bleeds without an obvious injury, forms a persistent crust, or creates a new sore. Seek earlier review when these changes occur together or when the spot is unlike your other moles.

A regression description on a report is not, by itself, an emergency. The appropriate timing depends on the lesion's appearance and evolution, so follow the review interval given by your dermatologist and return sooner if new changes appear.

Useful questions include: Which features in this lesion represent regression? Do you recommend a comparison image, a follow-up examination, or removal? What specific change should prompt an earlier appointment? If removal is advised, what will the laboratory examination clarify?