What should you know about hepatitis C virus HCV antibody?

HCV stands for hepatitis C virus. Non-reactive means antibodies were not detected in the sample. Reactive means antibodies were detected, which can follow a current infection or an infection that the body cleared. The antibody test does not measure the amount of virus and does not grade liver scarring.

If exposure was recent, antibodies may not yet be detectable. A clinician may use a virus test and review the timing of exposure. Hepatitis C can be present without obvious symptoms; fatigue, nausea or discomfort under the ribs can occur in some people.

Discuss a reactive HCV antibody result with a GP. Ask about confirmatory RNA or viral load testing and an assessment of liver health, including whether a liver function test is suitable. Share a list of medicines, supplements and previous treatments. Do not donate blood or share blood-contact items until a clinician explains your result.

Arrange review after a reactive test, possible blood exposure or symptoms that concern you. Get urgent care for confusion, vomiting blood, black stools, severe abdominal pain, yellowing that is rapidly worsening or inability to keep fluids down.

Ask whether your result is reactive or non-reactive, whether the sample was taken at the right time, which test checks current infection, and how follow-up will protect your liver health.