What should you know about fusidic acid for impetigo?

Impetigo is a contagious surface infection that can produce blisters, sores, and yellow-brown crusts. Fusidic acid works against susceptible bacteria at the treated skin surface; it is not a general cream for every crust or rash. A clinician may choose a different treatment when infection is widespread, recurrent, deep, or not responding.

Keep the medicine away from the eyes, inside the nose, and mouth unless specifically instructed. Irritation, redness, itching, or a rash can occur where it is applied.

Follow the prescribed amount and schedule, and wash your hands before and after application. Gently clean away loose crusts with water, pat dry, then apply a thin layer to the affected area. Do not share towels, clothing, cosmetics, or the tube; cover sores as advised and wash bedding and clothing regularly.

Use the full course directed by the prescriber. Do not put fusidic acid on eczema, acne, or an unexplained rash simply because it is crusted. For broader treatment context, read [Topical Antibiotic Therapy](/treatments/medical-dermatology/topical-antibiotic-therapy/) and [Antibiotics For Skin Infection](/treatments/medical-dermatology/antibiotic-therapy-for-skin-infection/).

Seek prompt medical advice if redness spreads, pain or swelling increases, fever develops, the eye area is involved, or sores become extensive. Contact the prescriber if the skin worsens, a new reaction appears, or there is no clear improvement after the instructed course. [Crusting Skin](/symptoms/skin-crusting/) may have causes other than impetigo.

Ask whether the appearance fits impetigo, how much cream to apply, whether close contacts need advice, and what to do if the infection returns. Mention allergies, pregnancy, breastfeeding, and any other creams or antibiotics you use.