What should you know about glabridin hyperpigmentation?

Glabridin is a compound derived from liquorice that is used in some brightening products. It is discussed because it may influence tyrosinase activity and inflammatory signals involved in melanin production. Hyperpigmentation has many possible triggers, including sun exposure, acne or eczema inflammation, hormonal changes and irritating products. Treating the wrong cause can prolong discolouration, so an ingredient label cannot replace a skin examination.

Use a gentle cleanser, moisturiser and broad-spectrum sunscreen, since ultraviolet and visible light can deepen some dark patches. Introduce a glabridin product gradually and stop if burning, swelling or a rash develops. A dermatologist can decide whether a prescription such as hydroquinone treatment, a chemical peel, skin brightening treatment, IPL photofacial or picosecond laser treatment is appropriate. The choice depends on pigment depth, skin tone, the cause and the risk of irritation or rebound darkening.

Arrange a clinical review if a patch is new, rapidly changing, uneven in colour, bleeding, crusting, painful or different from nearby marks. Seek help sooner if pigmentation follows a severe reaction or procedure and is accompanied by blistering, infection signs or escalating pain. Do not keep adding brightening products to a worsening rash.

Ask what is causing the pigmentation, whether glabridin suits your skin, how to patch-test it, and how long to trial it before reassessment. Discuss sun protection, prescription options, procedure-related risks and what symptoms mean you should stop treatment.