What to know about Differin cream

Adapalene is a topical retinoid that helps keep dead skin cells from building up inside pores. The cream base may feel more comfortable for some people with dry skin, but it can still cause redness, tightness, peeling, or burning. These effects are more likely when too much is applied or when several strong products are combined.

Cleanse gently, let the face dry fully, then smooth a small amount over the affected area. Do not use extra cream to speed the process, and avoid the eyelids, mouth corners, nostrils, broken skin, and sunburn. Add a simple moisturizer if needed and use sun protection during the day. Introduce other exfoliating acids, scrubs, waxing, or irritating treatments only after checking that they fit your plan. Follow the package or prescriber instructions if they differ from general guidance.

Stop and seek medical advice for severe burning, blistering, facial swelling, or a rash that extends beyond the application area. Get emergency help for swelling of the lips or tongue or difficulty breathing. Book a review if acne is forming deep tender lumps, leaving marks or scars, or remaining troublesome despite careful use.

Ask how the cream differs from another adapalene formulation, how often to apply it at first, which products to avoid, and what improvement should be monitored.