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Differin gel: what to know before using it

Adapalene and where it is used in the body
Illustration: Adapalene and where it is used in the body

Short answer

Differin gel contains adapalene, a topical retinoid that helps regulate clogged pores but can cause dryness and irritation.

This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.

At a glance

Ingredient
Adapalene
Primary action
Regulates follicular cell shedding
Common reaction
Dryness, redness, peeling, or stinging

What the gel does

Adapalene acts in hair follicles, where it helps normalise the shedding of skin cells and can reduce the formation of comedones. It is used on acne-prone skin rather than as a spot treatment for only visible blemishes. Early dryness, redness, peeling, or stinging can happen as the skin adjusts. These reactions do not mean you should apply more; excess product is more likely to irritate than speed improvement.

How to use it carefully

Follow the directions supplied by your clinician or pharmacist. Apply a thin layer to clean, completely dry skin and keep it away from the eyes, lips, nostrils, and cuts. Use moisturiser, avoid harsh scrubs and strongly irritating products, and protect your skin from sunlight. If your skin is sensitive, ask whether a gradual schedule is suitable. Mention other acne medicines, eczema, allergies, pregnancy, or plans to conceive before starting.

When to seek care

Get medical advice for facial swelling, hives, blistering, severe burning, or a rash that spreads. Arrange a review if irritation prevents normal washing or continues despite pausing as advised. Seek help for severe or scarring acne, painful nodules, or an uncertain diagnosis instead of repeatedly increasing the gel.

Questions for your doctor

Is adapalene appropriate for my type of acne? How much should I use and how can I manage peeling? Which products should I avoid alongside Differin gel, and when should my progress be reviewed?

Find care

General Clinics & Polyclinics in Abu Dhabi

That answer is general. If you want it applied to your own case, these are licensed general clinics & polyclinics listed in Abu Dhabi.

City

Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.

A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.

Questions people ask

Should I put Differin gel only on spots?

It is commonly used as a thin layer over the acne-prone area as directed, rather than as a heavy application to individual spots.

Can I use other exfoliants with Differin gel?

Combining irritating products can worsen dryness, so ask a clinician or pharmacist before adding acids, scrubs, or another retinoid.

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Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.