Why is an inactivated vaccine used in hepatitis A vaccination?

Hepatitis A affects the liver. In an inactivated vaccine, the virus has been treated so it cannot multiply in the person receiving the vaccine. The body can recognise its components and make an immune response, including immune memory.

Vaccination is one part of preventing hepatitis A. Careful hand hygiene and safe food and water choices remain relevant, particularly when travelling or in settings where exposure may be more likely. A clinician can explain which doses are advised for your circumstances.

Bring your vaccination record if you have one. Mention previous vaccine reactions, allergies, pregnancy, liver disease, a weakened immune system, and any planned travel. The clinician can check whether you have already had doses and make a plan that fits your timing.

Do not rely on vaccination alone if you may have had a recent exposure to hepatitis A. Contact a clinician promptly, because the appropriate next steps depend on when the exposure occurred and your health history.

Seek urgent care for breathing difficulty, throat or facial swelling, widespread hives, or collapse after a vaccine. Arrange prompt assessment for yellowing of the skin or eyes, dark urine, severe abdominal pain, repeated vomiting, or marked weakness, whether or not you have been vaccinated.

Ask how many doses are recommended for you, when each should be given, and whether an upcoming trip changes the timing. You can also ask how to recognise a significant vaccine reaction and who to contact after the appointment.