What is topical calcineurin inhibitors done with?

Tacrolimus ointment and related medicines calm immune activity in the skin. They may be prescribed for eczema or other inflammatory conditions when a steroid-free option is useful, including on areas where repeated steroid exposure needs careful planning. They do not treat every rash, and they should not be applied to an undiagnosed infection. Mild warmth, stinging, or itching can occur at first and often matters less as the skin settles.

Apply a thin layer to the affected skin as prescribed, avoiding the eyes, mouth, and broken skin unless specifically instructed. Wash hands after application and use moisturiser according to the treatment plan. Protect treated skin from excessive sunlight and avoid tanning devices. Tell the clinician about infection, cold sores, pregnancy, immune problems, or medicines that affect immunity. Do not add a steroid, antibiotic, or antiseptic cream without checking the plan.

Contact the prescriber if burning is severe, persistent, or accompanied by swelling, blistering, or a spreading rash. Seek prompt medical advice for pus, fever, painful grouped blisters, or rapidly worsening redness, because infection can need different treatment. Eye pain, vision change, facial swelling, or breathing difficulty needs urgent assessment.

Ask which areas should receive tacrolimus, whether moisturiser goes before or after it, how to handle a flare, and which symptoms would mean the diagnosis or treatment needs review.