What Is the First Treatment for Melanoma?

Excision removes the melanoma with a margin of surrounding skin so a laboratory can assess the tumour and the edges of the specimen. The next step depends on features such as depth, margins, and whether there is evidence of spread. [Melanoma](/conditions/melanoma/) care therefore follows the pathology report rather than a single plan for every person.

Do not delay a specialist appointment while waiting for a changing mole to settle. Ask whether the initial procedure will also provide the tissue needed for staging, and whether a [Sentinel Lymph Node Biopsy](/treatments/diagnostics-and-staging/sentinel-lymph-node-biopsy/) is relevant. If further disease is found, the team may discuss wider [Skin Cancer Surgery](/treatments/surgical-dermatology/skin-cancer-surgery/), [Immunotherapy](/treatments/systemic-therapy/immunotherapy/), or [Targeted Therapy](/treatments/systemic-therapy/targeted-therapy/).

Seek prompt dermatology review for a changing mole or spot with asymmetry, an irregular border, varied colour, growth, bleeding, crusting, or persistent itching. Seek urgent care for uncontrolled bleeding, rapidly spreading redness, severe pain, or signs of infection after surgery.

What did the pathology report show, and are the margins clear? Do I need further [Tumour Removal Surgery](/treatments/surgical-oncology/tumour-removal-surgery/)? How will follow-up be organised through [Follow-Up After Cancer Treatment](/treatments/survivorship-and-rehabilitation/post-treatment-surveillance/)?