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What is the first treatment for endometrial hyperplasia?

How the structures involved in Endometrial Hyperplasia differ from normal
Illustration: How the structures involved in Endometrial Hyperplasia differ from normal

Short answer

The first treatment for endometrial hyperplasia is often progesterone, provided as tablets or through a hormonal coil.

This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.

At a glance

Common first approach
Progesterone treatment
Key test
Endometrial biopsy

How treatment works

Endometrial hyperplasia means the womb lining has become thicker than expected. Progesterone counteracts oestrogen’s effect and can help the lining become thinner. The best option depends on whether atypical cells are present, how much bleeding you have, your future pregnancy plans and other health conditions.

An endometrial biopsy is used to examine lining cells and identify changes that need closer treatment. Follow-up sampling may be recommended to check how the lining responds. A hysterectomy may be discussed when atypical hyperplasia persists, returns, or when medication is not suitable, especially if pregnancy is not desired.

What to do next

Ask a gynaecologist which type of hyperplasia was found and whether a biopsy has provided enough information. Discuss progesterone tablets or a hormonal coil, expected bleeding changes, contraception and follow-up appointments. Do not stop prescribed hormone treatment without speaking with the clinician who arranged it.

When to seek care

Arrange medical review for bleeding between periods, after sex, after menopause, or bleeding that becomes heavier or prolonged. Seek urgent care if bleeding causes faintness, severe weakness, chest discomfort or shortness of breath.

Questions for your doctor

Does my biopsy show atypical cells? Which progesterone option fits my plans? How will response be checked? When would a hysterectomy be recommended? Could treatment affect pregnancy, contraception or bleeding patterns?

Questions people ask

Can endometrial hyperplasia improve without surgery?

Some forms can respond to progesterone, with follow-up checks to assess the lining. The biopsy result determines how closely it should be monitored.

What does a hormonal coil do?

It releases progesterone inside the womb and may reduce overgrowth and heavy bleeding while providing contraception.

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Second opinions are routine in cancer care and asking for one does not affect your treatment. How to arrange a second opinion in the UAE.

Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.

A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.

Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.