What is GnRH agonist drugs used for?

These medicines first stimulate, then desensitise, the pituitary hormone pathway. With continued treatment, the body receives less of the signal that prompts the ovaries or testes to make sex hormones. The resulting hormone reduction can slow the growth of some hormone-sensitive cancers.

In oncology, GnRH agonists may be used in prostate cancer care and in selected breast cancer plans, depending on the person's situation. They may be given by injection at an interval chosen by the treating team. The medicine is one part of a wider plan and may be combined with other systemic treatments.

Keep appointments for each dose and tell the team about heart conditions, bone problems, diabetes, mood changes, and medicines or supplements. Ask how hormone changes may affect hot flushes, sexual health, fertility, muscle, and bone health. Do not stop or delay doses without discussing it with the prescriber.

Report severe or persistent pain, marked mood change, new weakness, swelling, or troublesome symptoms after an injection. Seek urgent help for chest pain, severe breathlessness, fainting, sudden confusion, or signs of a serious allergic reaction such as facial swelling or difficulty breathing.

Ask what hormone signal the medicine is targeting, when its effect should begin, how side effects will be monitored, and whether bone, heart, metabolic, or fertility support is appropriate.