What should you know about Profhilo for nasolabial folds?

Short answer
Profhilo may improve skin hydration and texture around nasolabial folds, but it is not designed to replace the structural support of a dermal filler.
This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.
At a glance
- Main role
- Skin hydration and texture support
- Key limitation
- It is not a targeted fold-filling treatment
- Assessment
- The surrounding mid-face should be examined
What this means for smile lines
Nasolabial folds run from the sides of the nose towards the corners of the mouth. Their appearance can reflect changes in skin quality, facial volume, and the way facial tissues move. Profhilo is an injectable hyaluronic-acid treatment intended to spread through the skin and support a smoother, more hydrated appearance. It does not work like a conventional filler placed within a fold to create targeted volume.
A clinician may therefore discuss Profhilo when laxity or crepey texture is part of the concern. If the fold is deep or linked to loss of support in nearby areas, dermal fillers or another approach may be considered instead or alongside it. A treatment plan should match the cause of the visible fold, not simply the location of the line.
How to approach a consultation
Choose a qualified medical injector who examines the whole mid-face and asks about previous injectables, allergies, medicines, active skin problems, and any history of unusual swelling. Ask whether the proposed product and injection pattern are intended to improve texture, volume, or both. Before treatment, clarify the expected visible change, number of visits, aftercare, and what happens if the result is uneven or insufficient.
Avoid booking injections through an unclear provider or while the skin near the injection sites is inflamed or infected. Follow the clinic's instructions about makeup, exercise, heat, and medicines. Mild tenderness, swelling, or small bumps can occur after injections; do not massage the area unless the treating clinician specifically tells you to.
When to seek medical care
Contact the treating clinic promptly if swelling is worsening, pain is severe, the skin becomes increasingly red or hot, or you develop discharge or fever. Seek urgent medical help for sudden vision changes, severe unusual pain, marked skin colour change, weakness, or trouble speaking after an injection. These symptoms need assessment rather than home treatment.
Questions for your doctor
Ask: Is Profhilo suitable for the texture and support changes I have? Would a dermal filler, collagen biostimulator injection, or thread lift address the concern more directly? Where would you inject, what result is realistic, and how will you manage swelling or an uneven result?
Find care
General Clinics & Polyclinics in Abu Dhabi
That answer is general. If you want it applied to your own case, these are licensed general clinics & polyclinics listed in Abu Dhabi.
27 Ar Ruwwad St - Shakhbout City - MSH4 - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, MetLife +20 more
Al Ruwais, Al Dhafrah
Accepts: Daman, Thiqa, AXA, Cigna +16 more
Al Bahyah - Al Bahyah Old - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, Allianz Care +18 more
Abu Dhabi
Accepts: Daman, Thiqa, AXA, Cigna +27 more
Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.
A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.
Questions people ask
Can Profhilo remove nasolabial folds?
It may soften the look of folds when skin quality is part of the concern, but it does not reliably erase a pronounced fold or provide the same structural support as a dermal filler.
Is Profhilo the same as a dermal filler?
No. Both may involve hyaluronic acid, but Profhilo is used for a different treatment purpose and is not simply injected as a conventional volume replacement inside a fold.
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Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.