What should you know about a pheochromocytoma urine test?

A pheochromocytoma urine test checks a collected urine sample for hormone breakdown products released by an adrenal tumour. Clinicians may request it when episodes such as pounding headaches, sweating, a racing heartbeat or raised blood pressure need investigation. The result is interpreted with your symptoms, medicines and other tests.

The sample may be collected over a set period or provided as a spot sample, depending on the laboratory request. An abnormal result does not by itself prove pheochromocytoma. Stress, illness, strenuous activity, caffeine, nicotine and some medicines can affect hormone measurements. A clinician may repeat the test or arrange blood testing and imaging before making a diagnosis.

Follow the collection instructions closely, keep the container clean and return it as directed. Tell the clinician about every prescription, supplement and non-prescription medicine before changing anything; some treatments should not be stopped without supervision. Ask whether you need to avoid particular foods, drinks or activities before sampling. A general urine test is a different examination; learn more about a [Urine Test](/treatments/diagnostics-and-screening/urine-test/).

Seek emergency help for severe chest pain, fainting, severe breathlessness, confusion, a sudden severe headache or very high blood pressure with neurological symptoms. These signs need prompt assessment regardless of whether a urine test has been arranged. For non-urgent questions about collection or results, contact the requesting clinic.

Ask why this test is recommended, which medicines or supplements might interfere, how the sample should be stored, when results are expected and what follow-up test would be considered if the result is abnormal.