What should you know about nasal lymphoma?

Lymphoma is a cancer of lymphatic cells. When it involves the nasal cavity or sinuses, it may cause persistent blockage, nosebleeds, discharge, facial pressure, reduced smell or swelling. These symptoms can also result from infection, allergies or other nasal conditions, so symptoms alone cannot identify lymphoma.

A biopsy is usually needed to identify the lymphoma subtype. Further tests can show whether disease is limited to the nasal area or involves other parts of the body. A PET-CT scan may be included in staging. Night sweats, fever or unexplained weight change can be relevant symptoms, but they are not specific to lymphoma.

Arrange assessment with an ear, nose and throat specialist and a haematology or oncology team. Bring information about symptom timing, previous infections, medicines and any immune-system conditions. Treatment may include chemotherapy, immunotherapy, radiotherapy or a combination, selected for the lymphoma subtype and stage.

Some people with lymphoma that returns or does not respond to initial treatment may be assessed for cellular treatment or an autologous stem cell transplant. Learn more about [Lymphoma](/conditions/lymphoma/), [PET-CT Scan](/treatments/diagnostics-and-staging/pet-ct-scan/) and [Chemotherapy](/treatments/systemic-therapy/chemotherapy/).

Seek prompt medical review for a persistent blocked nostril, recurrent nosebleeds, facial swelling, worsening pain, reduced vision or a new lump in the neck. Get urgent help for uncontrolled bleeding, severe breathing difficulty, confusion, or sudden changes in vision.

Which lymphoma subtype is present? Where is it located, and what tests are needed to stage it? What treatment is recommended first, and what side effects should be reported? When might radiotherapy, immunotherapy, cellular therapy or transplant be considered? How will nasal function and treatment response be monitored?