MMR and varicella together side effects

The injection site may feel tender or look slightly red. Some people feel tired or develop a mild fever. A small, short-lived rash can appear as the immune system responds to the weakened vaccine viruses. These effects do not mean that the person has ordinary measles, mumps, rubella, or [Chickenpox](/conditions/chickenpox/).

Symptoms can also come from another infection or an unrelated skin problem. Note when the reaction started, where it is located, whether it is spreading, and whether breathing, alertness, or fluid intake has changed. This record helps a clinician interpret the pattern.

Encourage rest and regular fluids. Keep the injection area clean and avoid vigorous rubbing. Ask a pharmacist or clinician which fever or pain medicine is suitable; use it according to their instructions. Do not burst blisters. If itching is troublesome, ask whether [Antihistamine Treatment](/treatments/medical-dermatology/oral-antihistamine-therapy/) is appropriate. A [GP Consultation](/treatments/consultations-and-assessment/gp-consultation/) can assess a reaction that is not settling.

Get emergency help for difficulty breathing, swelling of the lips, tongue, or throat, widespread hives with weakness, or collapse. Contact a clinician for a persistent [Fever](/symptoms/fever/), severe headache, unusual drowsiness, dehydration, or extensive [Skin Blisters](/symptoms/skin-blisters/). Do not wait for a rash to become severe before seeking advice if the person is vulnerable or unwell.

Ask which symptoms are expected for this vaccine visit, how long monitoring should continue, and what treatment is suitable for fever or itching. Ask whether a history of [Shingles](/conditions/shingles/) or chickenpox changes future vaccination advice.