What should you know about injectable GLP-1 receptor agonists?

GLP-1 receptor agonists act on signals involved in insulin release, appetite and the movement of food through the stomach. Some are prescribed for type 2 diabetes, and some may be prescribed for weight management when clinically appropriate. They are not suitable for everyone. Nausea, vomiting, diarrhoea, constipation, reduced appetite and injection-site irritation can occur, especially when treatment starts or the dose changes. The medicine and dose should be chosen by a qualified clinician.

Use the medicine exactly as prescribed and learn how to store, prepare and dispose of the device. Keep a record of doses and tell your clinician about diabetes medicines, pregnancy or plans for pregnancy, gallbladder disease, pancreatitis, kidney problems, and severe digestive symptoms. Eat and drink according to your care plan, particularly if nausea reduces intake. Do not combine products or change the dose without medical advice. A missed dose needs product-specific instructions.

Seek urgent help for severe or persistent abdominal pain, repeated vomiting, faintness, confusion, trouble breathing, facial swelling, or signs of a serious allergic reaction. If you use other glucose-lowering medicines, ask what low blood glucose feels like and what action to take. Contact your prescriber when side effects prevent fluids or food, or when symptoms are getting worse rather than settling.

Ask what the medicine is intended to improve, how progress will be checked, how to handle a missed dose, and which symptoms require urgent review. Confirm storage instructions and whether any current medicine should be adjusted.