What should you know about infectious mononucleosis hepatitis?

Infectious mononucleosis, also called [Glandular Fever](/conditions/glandular-fever/), can cause inflammation in the liver while the immune system responds to the infection. Some people have tiredness, fever, sore throat and swollen glands; others notice nausea, reduced appetite or discomfort under the right ribs. [Fatigue](/symptoms/fatigue/) may continue after throat symptoms improve.

A clinician may use an examination and blood tests to assess the liver and track recovery. Liver irritation can occur without obvious symptoms, so avoid assuming that feeling better means all activity and medicines are suitable.

Rest, drink regularly and return to normal activities gradually. Avoid alcohol and check every medicine, supplement or herbal product with a clinician or pharmacist because some can add strain to the liver. Avoid contact sports and heavy exertion until a clinician confirms that returning is sensible, particularly if the spleen may also be enlarged.

Keep follow-up appointments if liver blood tests are planned. Record changes such as worsening [Feeling Generally Unwell](/symptoms/feeling-generally-unwell/), appetite loss, abdominal discomfort or yellowing of the skin or eyes.

Seek urgent help for severe or increasing abdominal pain, confusion, unusual bleeding, repeated vomiting, yellow skin or eyes, very dark urine, or inability to drink. Emergency care is appropriate for sudden severe pain in the upper abdomen, breathing difficulty or collapse.

Arrange medical review for persistent [Fever](/symptoms/fever/), worsening [Sore Throat](/symptoms/sore-throat/), marked weakness or [Night Sweats](/symptoms/night-sweats/) with other concerning symptoms.

Ask which liver tests are needed, which medicines and activities to avoid, when exercise can resume, and which symptoms require same-day assessment.