How is glioblastoma treated?

Brain tumour surgery may remove as much visible tumour as can be taken safely. The surgeon balances tumour removal with protection of speech, movement, vision and other brain functions. Tissue from the operation is examined to confirm the diagnosis and identify molecular features that help guide the plan.

Radiotherapy is directed at the area at risk of microscopic tumour cells. Chemotherapy may be given during or after radiotherapy, depending on the treatment plan. Some people are offered a clinical trial, which may test a new medicine, device or treatment combination. Support for seizures, swelling, fatigue, movement, speech and memory is part of care.

Ask for a clear medicines schedule and advice about driving, work, exercise and seizure safety. Keep a list of symptoms and treatments, including steroids or anti-seizure medicine. A persistent headache or a first-time seizure needs medical assessment; do not assume it is caused by glioblastoma without testing.

Call emergency services for a seizure lasting several minutes, repeated seizures without recovery, sudden weakness, new trouble speaking, severe confusion or loss of consciousness. Contact the oncology team promptly for worsening headache with vomiting, fever after surgery, a change in alertness or a new neurological symptom.

What can surgery safely remove, and what functions could it affect? What do the pathology and molecular results mean? When will radiotherapy and chemotherapy begin? Which symptoms suggest swelling or recurrence? Is a clinical trial appropriate for me?