Hives With Angioedema: What to Know

Hives are raised, itchy areas on the skin. Angioedema is swelling deeper beneath the skin, often affecting the lips, eyelids, hands, feet, or other soft tissues. The swelling may feel tight or warm rather than itchy and can last longer than an individual welt. Hives may present with angioedema, but either symptom can also occur separately.

Possible triggers include an allergic exposure, an infection, or a medicine. The combination does not identify the trigger by itself. Write down what happened before the episode and whether there was [Skin Swelling](/symptoms/skin-swelling/) elsewhere.

Move away from a suspected exposure, avoid scratching, and use a cool compress if it is comfortable. Do not take a medicine that has caused a previous reaction unless a qualified clinician has specifically instructed you to do so. A clinician may recommend an [Antihistamine Treatment](/treatments/medical-dermatology/oral-antihistamine-therapy/). Photograph the skin and record the onset, affected areas, foods, medicines, and any breathing or stomach symptoms.

Seek emergency help immediately for swelling of the tongue, mouth, or throat; trouble breathing or swallowing; wheezing; faintness; confusion; or rapidly worsening symptoms. Do not wait for the skin welts to settle. Even when breathing is normal, new or repeated angioedema needs medical assessment to review triggers and future precautions. Severe or persistent symptoms may require treatment chosen by a clinician, sometimes including [Oral Corticosteroid Treatment](/treatments/medical-dermatology/oral-corticosteroid-therapy/).

Ask whether the swelling pattern is angioedema, which triggers or medicines need review, what to do if the mouth or throat becomes swollen, and whether you need a written emergency plan. Mention family history and earlier episodes.