What should you know about high mosaic embryo transfer?

Mosaic means the tested sample showed a mixture of cells with different chromosome findings. High mosaic means the atypical finding made up a larger share of that sample. The result describes the sampled cells, not a complete examination of the embryo, and it does not by itself establish whether a pregnancy will develop normally.

A fertility specialist and a genetic counsellor can explain the chromosome involved, how the laboratory classified the result, and whether other embryos or testing options exist. They can also discuss prenatal diagnostic testing if pregnancy occurs.

Ask the clinic to review the report with you rather than relying on the label alone. Discuss the embryo’s grading, the laboratory method, the chromosome finding, and whether transfer, further treatment or using another embryo fits your circumstances. If transfer is chosen, ask how pregnancy will be monitored and which prenatal tests will be offered.

Before treatment, check whether micronised progesterone is part of your prescribed preparation and how to use it. Do not change fertility medicines without the clinic’s instructions.

Contact your fertility team promptly for heavy bleeding, severe or worsening abdominal pain, faintness, fever, or breathlessness after a procedure or during early pregnancy. These symptoms need clinical assessment and should not be explained away by the embryo result.

Which chromosome finding was reported, and how was the mosaic category defined? What are the limitations of this test? What alternatives are available, and what follow-up would be recommended after transfer?