Fatigue, loss of appetite and nausea

Gastroenteritis commonly presents with nausea, reduced appetite, diarrhoea, vomiting, cramps, or fever. Gastritis and peptic ulcer disease can present with nausea, upper-abdominal pain, burning, or discomfort after eating. Influenza and COVID-19 may present with fatigue and nausea alongside fever, aches, cough, sore throat, or altered smell. Depression can present with low energy and appetite changes, sometimes without digestive symptoms. Hepatitis A may present with fatigue, nausea, poor appetite, abdominal discomfort, dark urine, or jaundice. Pancreatic cancer can present with persistent appetite loss, fatigue, abdominal or back pain, or jaundice, although these symptoms have many other explanations. A symptom pattern cannot confirm a diagnosis by itself.

Take frequent small sips of water or an oral rehydration drink, especially after vomiting or loose stools. When tolerated, try bland or familiar foods in small amounts; avoid forcing a large meal. Note triggers, timing, urine output, bowel symptoms, fever, pain, medicines, and whether anyone nearby is ill. Rest and avoid driving or hazardous work if dizziness or marked weakness is present. Book a primary-care review when symptoms continue, recur, or make normal eating and drinking difficult.

Get urgent help for severe abdominal pain, persistent vomiting, confusion, fainting, breathing difficulty, blood in vomit or stool, or inability to keep fluids down. Very little urine, a dry mouth with worsening weakness, or dizziness on standing can signal dehydration. Seek prompt assessment for yellow eyes or skin, dark urine, unplanned weight loss, or a persistent fever.

Which features make infection, stomach irritation, medicine effects, or another cause more likely? Do I need an examination or tests? What should I drink and eat while nausea continues? At what point should I seek urgent care?