What should you know about embryo glue frozen transfer?

The name refers to a laboratory medium containing hyaluronan, a substance found naturally in the reproductive tract. The embryo is placed in this medium before it is loaded into the catheter. The medium is intended to support contact between the embryo and the uterine lining; it is not a household adhesive and does not stick the embryo in place.

A frozen transfer uses an embryo stored after earlier treatment. The clinic prepares the uterine lining in a natural or hormone-supported cycle, then times the transfer to the embryo’s developmental stage. Embryo glue may be offered as an optional laboratory step, depending on the clinic and your treatment plan.

Ask whether the medium is recommended for your circumstances, when it will be used, and whether it changes the clinic’s usual transfer process. Follow the prescribed lining medicines exactly; some plans include Micronised Progesterone. On transfer day, take medicines as directed, arrive with the bladder preparation requested by the clinic, and allow time for the appointment.

After the procedure, continue the medicines until the clinic gives you a different instruction. Ordinary gentle activity is usually compatible with recovery, but your own team may set limits based on your history. A home pregnancy test taken too early can be misleading, so use the testing date provided by the clinic.

Contact the fertility clinic promptly for heavy bleeding, worsening pelvic pain, fever, faintness, breathing difficulty, or marked abdominal swelling. These symptoms need assessment rather than being judged by whether embryo glue was used. Seek urgent care for severe pain, collapse, or difficulty breathing, and tell the clinicians that you recently had a fertility procedure.

Ask what evidence supports using embryo glue in your planned frozen transfer, what medium is used, whether there is an additional laboratory charge, and how your embryo and lining will be assessed before transfer.