Bordetella pertussis antibiotic treatment: what to know

Pertussis is a bacterial respiratory infection. A clinician chooses an antibiotic after considering symptoms, test results, age, allergies, pregnancy, and contact with vulnerable people. Treatment can lower the chance of passing infection to others, especially when given early. The cough may continue because the airways remain irritated after the bacteria have been controlled.

Take the medicine exactly as prescribed and tell the clinician about other medicines or a previous antibiotic reaction. Do not share leftover tablets or stop early without advice.

Arrange medical advice promptly if pertussis is suspected, particularly when a baby, pregnant person, or someone with a long-term illness is nearby. Limit close contact while following local medical advice, cover coughs, wash hands, and improve airflow indoors. A household or close contact may need separate advice about preventive treatment.

For comfort, rest, sip fluids, and avoid smoke or other airway irritants. Read more about [Antibiotic Treatment](/treatments/medical-management/antibiotic-treatment/) and [Whooping Cough](/conditions/whooping-cough/).

Seek urgent help for trouble breathing, pauses in breathing, blue or grey lips, repeated vomiting with inability to drink, marked drowsiness, or signs of dehydration. Infants with coughing spells or breathing changes need prompt assessment. A severe or worsening [Cough](/symptoms/cough/) also warrants medical review.

Ask whether testing is needed, which antibiotic is appropriate, when you can safely return to work or school, and whether close contacts need assessment. Ask what side effects require a call and how to manage the cough while it settles.