When is prescription antiperspirant recommended for pitted keratolysis?

Pitted keratolysis is a bacterial infection affecting the outer layer of the soles. Tiny pits, softened skin, and a noticeable odour can become more apparent when feet stay wet inside shoes. Prescription antiperspirant does not replace treatment directed at the infection; it reduces sweating so the skin is less damp. A clinician may consider it when moisture is a continuing trigger or when the condition keeps returning.

Arrange an assessment for smelly, macerated, or pitted soles, especially if the problem persists after changing socks and shoes. Keep feet clean and dry, rotate breathable footwear, change damp socks promptly, and avoid sharing towels or footwear. If prescribed antiperspirant, apply it only to dry, intact skin and follow the recommended timing. The clinician may also prescribe an antimicrobial treatment, because drying alone cannot clear the infection.

Seek care if pain, spreading redness, swelling, drainage, open cracks, or fever develops. A sore foot, diabetes, poor circulation, or reduced sensation lowers the threshold for prompt review. Return to the clinician if pits or odour persist after treatment, since another foot condition can look similar and may need a different approach.

Ask whether the pits are consistent with pitted keratolysis, which treatment targets the infection, how to reduce foot moisture safely, and how to prevent recurrence.