When is oophorectomy recommended for a BRCA gene mutation?

A BRCA mutation can raise the chance of ovarian, fallopian tube and related cancers. Removing both ovaries, usually with the fallopian tubes, lowers the amount of ovarian tissue at risk. The decision is preventive rather than a sign that cancer has been found. Timing depends on the specific gene, your personal and family history, whether you wish to become pregnant, and whether other risk-reducing surgery is being considered.

Removal of the ovaries before natural menopause causes an abrupt fall in ovarian hormones and ends the ability to release eggs. Your team can discuss fertility preservation, menopausal symptoms, bone health, heart health and whether hormone treatment is suitable for you.

Arrange a consultation with a gynaecological cancer specialist and a genetics professional. Take your genetic test report, family history and a list of medicines. Ask whether the fallopian tubes and ovaries should be removed together, whether the uterus also needs attention, and how surgery could affect fertility and menopause. If pregnancy is a future goal, ask about egg or embryo preservation before an operation. Read more about [Oophorectomy](/treatments/gynaecological-surgery/oophorectomy/).

A BRCA result itself is not an emergency, but contact your clinician promptly if you develop persistent abdominal swelling, pelvic pain, unusual vaginal bleeding, feeling full quickly or a change in bowel or bladder habits. After surgery, urgent assessment is needed for heavy bleeding, worsening severe pain, fever, breathlessness, chest pain, or a swollen painful leg.

Which BRCA gene change do I carry, and how does it affect the recommended timing? What are my fertility-preservation options? Would removing the fallopian tubes and ovaries be enough for my situation? How will you manage sudden menopause, and which symptoms should prompt a call after surgery?