When is genomic tumour profiling recommended for ovarian cancer?

Testing analyses ovarian tumour tissue for changes in genes and other molecular markers. The result may help the team discuss targeted treatment, maintenance treatment, immunotherapy, or a clinical option when appropriate.

Tumour testing and inherited genetic testing are different. A tumour result can sometimes suggest that inherited testing would be useful, but a specialist explains what the result means for you and, where relevant, your family.

Ask whether tissue from surgery or biopsy can be tested and whether the report will include markers relevant to your planned treatment. Testing may be revisited if the cancer returns or the treatment plan changes.

Bring any previous pathology or genetic reports to the appointment. Your oncologist will interpret the result with the cancer’s stage, response to treatment, other health conditions, and your goals.

Contact your cancer team urgently for severe or worsening abdominal swelling, persistent vomiting, inability to keep fluids down, heavy bleeding, sudden breathlessness, or fever during treatment. These concerns need clinical assessment rather than waiting for a test report.

Which tumour markers matter for my treatment? Is inherited genetic counselling also appropriate? What happens if the sample is inadequate? Could the result affect maintenance treatment or future options? Who will discuss the findings with me?