What to know about chemotherapy in older adults

Age alone does not determine whether chemotherapy is suitable. The team may review heart, kidney, liver, hearing, memory, mobility, nutrition, mood, and the ability to manage medicines. Existing conditions and interactions can change how treatment is given or monitored. Common effects include tiredness, nausea, appetite changes, mouth soreness, infection risk, and changes in blood counts. Some people need help with transport, meals, falls prevention, or appointments while recovering between cycles.

Bring an up-to-date list of prescription medicines, non-prescription products, and supplements, plus a trusted person if helpful. Tell the team about falls, numbness, hearing changes, memory concerns, weight loss, and support at home. Ask whether a geriatric assessment, pharmacist review, physiotherapy, nutrition advice, or home nursing would help. Keep a symptom diary and use only the medicines approved by the oncology team.

Contact the care team urgently for fever or chills, breathlessness, chest pain, confusion, a fall with injury, inability to drink, repeated vomiting, severe diarrhoea, or unusual bleeding. Sudden weakness or a new change in alertness also needs prompt assessment. Keep emergency and after-hours contact details where family or carers can find them.

Ask what benefit is expected, how treatment may affect independence, which medicines should change, what support is available at home, and how side effects will be handled between visits.