What is the first treatment for Paget disease of the breast?

Short answer
The first treatment tried for Paget disease of the breast is usually surgery, either a lumpectomy or a mastectomy depending on the area involved and whether cancer is found elsewhere in the breast.
This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.
At a glance
- Usual first treatment
- Surgery
- Main options
- Lumpectomy or mastectomy
How the choice is made
Paget disease affects the nipple and areola and can occur with an underlying breast tumour. Examination, mammography or other imaging, and a biopsy help define the diagnosis and extent. A lumpectomy removes the nipple-areola area and a margin of surrounding tissue while preserving much of the breast. A mastectomy removes the breast and may be advised when disease is widespread, when breast-conserving surgery would not remove it adequately, or when there are other findings that change the operation.
What to do next
Discuss the imaging and biopsy report with a breast surgeon. Ask where the disease is located, whether breast-conserving surgery is suitable, and whether additional treatment is expected after the operation. Talk through reconstruction, nipple appearance, recovery, and how the final laboratory report could affect the next decision.
When to seek care urgently
Before treatment, seek prompt assessment for a new nipple wound, bloody discharge, a rapidly changing breast area or a new lump. After surgery, contact the care team for fever, spreading redness, increasing swelling, wound opening, uncontrolled pain or sudden breathlessness.
Questions for your doctor
Is there an underlying tumour on my imaging or biopsy? Could lumpectomy remove all affected tissue? What would make mastectomy the safer choice? Will I need further treatment after surgery?
Questions people ask
Can Paget disease be treated without surgery?
Surgery is commonly used because the nipple-areola disease and any underlying tumour need to be removed and examined.
What determines the operation?
The underlying findings, how much breast tissue is involved and whether complete removal is possible with breast conservation guide the choice.
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Hospitals & Medical Centers in Abu Dhabi
Most UAE cancer care is delivered inside hospital services rather than by standalone oncology clinics, so these are licensed hospitals & medical centers listed in Abu Dhabi. Confirm the specific cancer service exists before you travel, and know that asking for a second opinion is routine.
Ahalia Hospital Musaffah Building - Musaffah - Musaffah Industrial - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, AXA, Cigna +26 more
Al Ruwais Industrial City - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, AXA, Cigna +30 more
Abu Dhabi, Abu Dhabi
Accepts: Daman, Thiqa, AXA, Cigna +30 more
Second opinions are routine in cancer care and asking for one does not affect your treatment. How to arrange a second opinion in the UAE.
Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.
A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.
Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.