What is the first treatment for mycosis fungoides?

Mycosis fungoides is a type of cutaneous T-cell lymphoma in which abnormal T cells affect the skin. The treatment plan depends on the confirmed diagnosis, the number and thickness of patches or plaques, the areas involved and whether there are signs beyond the skin.

Topical corticosteroids may reduce inflammation and itch in selected patches. Narrowband UVB phototherapy treats broader areas using controlled ultraviolet light and is often considered when lesions are thin or more widespread. PUVA therapy is another light-based option that may be used when the skin findings or treatment response call for it. These treatments require specialist supervision.

Use prescribed creams on the schedule provided and keep a record of itch, new patches and changes in thickness. Attend light-treatment appointments consistently and tell the team about medicines that increase light sensitivity. Moisturiser can support the skin barrier, but it does not replace lymphoma treatment. Avoid self-treating a persistent rash with strong products before diagnosis is confirmed.

Contact your specialist if patches spread quickly, become thicker, develop open areas, or cause a major change in itch or pain. Seek prompt assessment for enlarged lymph nodes, unexplained fever, drenching night sweats or unintended weight loss. These symptoms need medical evaluation and do not determine the diagnosis on their own.

Ask which skin-directed treatment matches your stage, why narrowband UVB phototherapy, PUVA therapy or a topical corticosteroid is being considered, and how response will be checked. Discuss light sensitivity, eye protection, cream application and which changes should trigger an earlier appointment.