What is the first treatment for metastatic breast cancer?

Metastatic breast cancer means breast cancer has travelled to another part of the body. The first plan is based on hormone receptors, HER2 status, where the cancer is present, how quickly symptoms are changing, and treatments used before. Hormone therapy can slow cancers driven by oestrogen or progesterone signals. Chemotherapy may be preferred when a faster body-wide response is needed or when the cancer is not hormone-sensitive. Bone-strengthening therapy may reduce skeletal problems when cancer affects bone, while palliative radiotherapy can ease pain from a particular area. Palliative care can be included at any stage to support comfort and function.

Ask whether a biopsy from a metastatic site is needed to recheck tumour markers, because these results can change treatment choices. Share the full history of breast cancer medicines, operations, radiotherapy, allergies, and other conditions. Tell the team about pain, breathlessness, weakness, appetite changes, or problems walking. Ask how the recommended treatment will be monitored and what to do if side effects affect eating, sleep, work, or movement. Keep a current medicines list and report supplements before systemic treatment begins.

Get urgent help for new severe breathlessness, chest pain, sudden weakness, confusion, a seizure, or loss of bladder or bowel control. Contact the oncology team promptly for new or worsening back pain, difficulty walking, a painful swollen limb, persistent vomiting, or fever during treatment. These symptoms can have several causes, but rapid assessment helps protect the spine, bones, and overall wellbeing.

What are my hormone-receptor and HER2 results? Is a new biopsy recommended? Why is this treatment the best starting point for my pattern of disease? Do I need bone-strengthening therapy or palliative radiotherapy? Which symptoms require an urgent call?