What causes ovarian hyperstimulation syndrome?

Short answer
Ovarian hyperstimulation syndrome is caused by an exaggerated ovarian response to fertility medicines that stimulate multiple follicles.
This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.
At a glance
- Main trigger
- A strong response to ovarian stimulation during fertility treatment
- Timing
- Symptoms can appear after treatment and may persist or intensify with pregnancy
What happens in the body
During some fertility treatments, medicines encourage several ovarian follicles to grow. A trigger medicine can then promote egg maturation and ovulation. In an unusually strong response, the enlarged ovaries release signals that make blood vessels more leaky. Fluid can move into the abdomen and, in more serious illness, affect circulation, breathing, or kidney function.
Symptoms may start after stimulation or become more noticeable after pregnancy begins, because pregnancy hormones can sustain the process. People with many developing follicles or a previous strong response may need particularly careful monitoring, but symptoms can occur despite planned treatment.
What to do
Follow the fertility clinic's monitoring and medicine instructions, keep track of weight changes, abdominal swelling, urine output, pain, nausea, and breathing, and maintain fluids as advised. Do not change fertility medicines or start self-treatment without contacting the clinic. The team may adjust treatment, arrange scans or blood tests, and recommend observation or hospital care according to symptoms.
When to seek care
Contact your fertility clinic promptly for increasing abdominal swelling, persistent vomiting, worsening pain, reduced urine, dizziness, or rapid breathing. Seek emergency care for severe breathlessness, chest pain, fainting, confusion, severe abdominal pain, or inability to keep fluids down. Early assessment helps identify fluid shifts, blood clots, and other complications.
Questions for your doctor
How strongly did my ovaries respond? Which symptoms should I report immediately? How will you monitor fluid balance and ovarian size? Should the treatment plan or timing of embryo transfer change?
Find care
General Clinics & Polyclinics in Abu Dhabi
That answer is general. If you want it applied to your own case, these are licensed general clinics & polyclinics listed in Abu Dhabi.
27 Ar Ruwwad St - Shakhbout City - MSH4 - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, MetLife +20 more
Al Ruwais, Al Dhafrah
Accepts: Daman, Thiqa, AXA, Cigna +16 more
Al Bahyah - Al Bahyah Old - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, Allianz Care +18 more
Abu Dhabi
Accepts: Daman, Thiqa, AXA, Cigna +27 more
Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.
A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.
Questions people ask
Can ovarian hyperstimulation syndrome happen without fertility treatment?
It is most commonly linked to fertility medicines, although rare spontaneous forms can occur and need medical assessment.
Is ovarian hyperstimulation syndrome the same as enlarged ovaries?
No. Enlarged ovaries can be part of the syndrome, which also involves fluid shifts and other body effects.
Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.