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What are the treatment options for paget disease of the breast?

How the structures involved in Paget Disease of the Breast differ from normal
Illustration: How the structures involved in Paget Disease of the Breast differ from normal

Short answer

Paget disease of the breast is usually treated with surgery, with lumpectomy or mastectomy selected according to the nipple changes, underlying breast findings and treatment goals.

This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.

At a glance

Main surgery choices
Lumpectomy or mastectomy
Decision factors
Underlying breast findings, extent and personal treatment goals

How the operation is chosen

Paget disease affects the nipple and areola and may occur with an underlying area of breast cancer. The team uses examination, breast imaging and tissue results to understand the extent of disease. Lumpectomy removes the nipple-areola area and the affected breast tissue while preserving much of the breast; radiotherapy may be discussed afterward when appropriate.

Mastectomy removes the breast and may be recommended when disease is extensive, involves several areas, or breast-conserving surgery would not provide a suitable result. Lymph-node assessment and other treatments may be considered when an underlying invasive cancer or other high-risk feature is found.

Preparing for treatment

Ask whether the nipple changes are isolated or linked with cancer elsewhere in the breast, and what the imaging and biopsy show. Discuss the expected breast shape, sensation, scars, recovery, reconstruction and whether radiotherapy or medicines may follow surgery.

Before surgery, share your medicines and health conditions with the team. Afterward, follow wound and drain instructions, protect the incision as advised, and mention increasing redness, fluid, swelling or arm movement problems.

When to seek medical help

Arrange prompt assessment for persistent nipple crusting, discharge, bleeding, inversion, a new breast lump, skin thickening or a change that does not settle. After treatment, seek urgent advice for fever, rapidly increasing breast swelling, severe pain, wound separation, heavy bleeding or sudden breathlessness.

Questions for your doctor

Is the disease limited to the nipple area? Would lumpectomy or mastectomy give the safer treatment plan? Will lymph nodes be assessed? Could I need radiotherapy or medicines afterward? What reconstruction and recovery choices are available?

Questions people ask

Does Paget disease always require removal of the whole breast?

No. Some people are suitable for breast-conserving surgery, while mastectomy is considered when the disease is more extensive or conservation is unsuitable.

What happens after surgery?

Follow-up may include wound review and discussion of radiotherapy, medicines, reconstruction or further treatment based on the final tissue findings.

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Second opinions are routine in cancer care and asking for one does not affect your treatment. How to arrange a second opinion in the UAE.

Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.

A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.

Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.