Tranexamic acid spot treatment: what to know

Topical tranexamic acid is applied to the skin rather than taken by mouth. It is used in some pigmentation routines, including care for melasma and marks that look darker than the surrounding skin. Darkening can have several causes, and a new or changing patch should not automatically be treated as cosmetic. A clinician can check whether the pattern fits pigmentation and whether another skin problem needs attention.

Use only the formulation recommended for your skin and follow its instructions. Apply it to clean, dry skin, keep it away from the eyes and broken areas, and introduce it carefully if your clinician advises. Daily broad-spectrum sun protection helps limit further darkening while treatment is being considered. Do not combine several irritating products at once, and stop if marked burning, swelling, or a spreading rash develops. Read more about [Tranexamic Acid](/materials/tranexamic-acid/) and [Tranexamic Acid for Melasma](/treatments/medical-dermatology/tranexamic-acid-for-melasma/).

Arrange a skin assessment for a spot that bleeds, crusts, becomes painful, changes quickly, or has an uneven appearance. Seek prompt help for facial swelling, breathing difficulty, or a severe reaction after application. Ask for medical advice before use if you are pregnant, breastfeeding, have very sensitive skin, or are already using prescription treatments.

Ask what is causing the pigmentation, which formulation suits your skin, where to apply it, and what other products should be paused. You can also ask how to recognise irritation and when the plan should be reviewed.