What should you know about porphyria cutanea tarda hepatitis c?

Porphyria cutanea tarda affects how the body handles porphyrins, substances involved in making haem. Porphyrin buildup can make exposed skin delicate, particularly on the backs of the hands, and blisters may form after sunlight. Hepatitis C is one condition associated with porphyria cutanea tarda; having the skin condition does not by itself prove that a person has hepatitis C. [Fatigue](/symptoms/fatigue/) can occur with hepatitis C, but some people have few or no symptoms.

Book a [GP Consultation](/treatments/consultations-and-assessment/gp-consultation/) for unexplained blistering, fragile skin or a known hepatitis C infection. Assessment may include blood tests for hepatitis C and a [Liver Function Test](/treatments/diagnostics-and-screening/liver-function-test/). Protect affected skin from sunlight, avoid picking blisters, and discuss alcohol, medicines and possible triggers with your clinician. Do not self-treat with supplements or stop prescribed medicines without advice.

Seek prompt care if blisters become red, hot, swollen or painful, or if you develop fever or discharge that may indicate infection. Get urgent help for yellowing of the skin or eyes, vomiting blood, black stools, severe confusion or unusual sleepiness. Widespread blistering or rapidly worsening skin damage also needs timely assessment.

Ask whether hepatitis C testing is appropriate, whether your liver needs monitoring, which medicines or exposures may worsen porphyria cutanea tarda, and how to protect healing skin.