What should you know about Mifegest and misoprostol?

Mifegest is a brand name that may refer to mifepristone. Mifepristone blocks progesterone activity, while misoprostol causes the uterus to contract and the cervix to open. Depending on the clinical situation, they may be used together or misoprostol may be used on its own.

The same medicine names can appear in different care pathways, including treatment after a miscarriage or induction of labour. The correct timing, route and follow-up depend on examination findings, pregnancy details and local clinical guidance. Do not rely on a product label or another person's instructions.

Tell the clinician about allergies, medicines, previous uterine surgery, severe anaemia, bleeding problems and any possibility of pregnancy outside the uterus. Confirm which medicine you have, how it is to be taken, what symptoms are expected and how follow-up will confirm that treatment is complete.

For background, see [Misoprostol](/materials/misoprostol/), [Medical Management of Miscarriage](/treatments/medical-gynaecology/medical-management-of-miscarriage/) and [Induction of Labour](/treatments/pregnancy-and-birth-care/induction-of-labour/).

Seek urgent medical care for heavy bleeding, fainting, severe or one-sided abdominal pain, shoulder-tip pain, breathing difficulty, fever, worsening illness or pain that is not controlled by the plan you were given. Contact your care team if bleeding or pain is not settling, if you cannot keep medicines down or if follow-up is unclear.

Ask what diagnosis is being treated, whether both medicines are needed, how to take each one, which symptoms are expected, what pain relief is suitable and when you need an examination or test.