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What should you know about melanoma merkel cell carcinoma?

How the structures involved in Merkel Cell Carcinoma differ from normal
Illustration: How the structures involved in Merkel Cell Carcinoma differ from normal

Short answer

Melanoma and Merkel cell carcinoma are different skin cancers, so a biopsy is needed to identify which one is present.

This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.

At a glance

Diagnosis
Biopsy and pathology distinguish these cancers.
Planning
The tumour site and staging guide treatment choices.

What the names mean

Melanoma develops from pigment-producing melanocytes. Merkel cell carcinoma develops from specialised cells in the skin and may appear as a firm, shiny or quickly growing lump, often on sun-exposed skin. Their appearance can overlap with harmless growths and other skin cancers, so the label cannot be confirmed by sight alone.

A pathology report examines cells from a biopsy. Doctors then assess the nearby lymph nodes and other areas when needed to understand whether the cancer is local or has spread. This information shapes the treatment conversation and follow-up schedule.

What to do next

Ask for a coordinated review with a dermatologist, surgeon or oncology team. Bring the pathology report and ask whether lymph-node assessment or scans are appropriate. Tumour Removal Surgery may remove the visible cancer and a margin of surrounding tissue. Radiotherapy may be advised for selected sites or risk patterns, while Immunotherapy can be considered in some settings. Your plan should reflect the confirmed cancer type, location and overall health.

When to seek care

Seek prompt review if a skin lump grows quickly, changes colour, bleeds, becomes tender or fails to heal. Call urgently for heavy bleeding, spreading redness with fever, severe pain, or new weakness or confusion. These signs do not prove cancer, but they need timely clinical assessment.

Questions for your doctor

Ask: Which cancer does the biopsy show? What margin and lymph-node checks are needed? Has staging found disease elsewhere? Would Radiotherapy or Immunotherapy add benefit? How should I examine the scar and nearby skin between visits?

Questions people ask

Can melanoma and Merkel cell carcinoma look alike?

Yes. Several skin conditions can resemble either cancer, which is why examination and tissue analysis matter.

What treatment might be used?

Depending on the findings, care may include surgery, Radiotherapy or Immunotherapy, sometimes in combination.

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Cancer care in the UAE

Hospitals & Medical Centers in Abu Dhabi

Most UAE cancer care is delivered inside hospital services rather than by standalone oncology clinics, so these are licensed hospitals & medical centers listed in Abu Dhabi. Confirm the specific cancer service exists before you travel, and know that asking for a second opinion is routine.

City
  • Ahalia Hospital Musaffah Building - Musaffah - Musaffah Industrial - Abu Dhabi - United Arab Emirates

    Accepts: Daman, Thiqa, AXA, Cigna +26 more

  • Al Ruwais Industrial City - Abu Dhabi - United Arab Emirates

    Accepts: Daman, Thiqa, AXA, Cigna +30 more

  • Abu Dhabi, Abu Dhabi

    Accepts: Daman, Thiqa, AXA, Cigna +30 more

Second opinions are routine in cancer care and asking for one does not affect your treatment. How to arrange a second opinion in the UAE.

Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.

A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.

Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.