Lebrest letrozole

After menopause, much of the body’s oestrogen is made when aromatase converts other hormones into oestrogen. Letrozole blocks this enzyme, reducing the hormonal signal that can encourage some breast cancer cells to grow. It is different from chemotherapy and is used only when its expected benefit fits the person’s diagnosis and treatment plan.

Possible effects include hot flushes, sweating, tiredness, headache, joint or muscle aches, mood changes, and vaginal dryness. Lower oestrogen can also affect bone strength and cholesterol, so monitoring may be part of care.

Take Lebrest exactly as prescribed and at a consistent time. Swallow the tablet as directed; do not change the dose, stop suddenly, or double the next dose after forgetting one without advice from your oncology team. Tell the team about other medicines, supplements, liver problems, bone problems, or a history of fractures. Keep appointments so symptoms, bone health, and the continuing value of treatment can be reviewed.

Get prompt medical advice for severe or persistent joint pain, a new fracture, marked weakness, or symptoms suggesting an allergic reaction such as facial swelling or trouble breathing. Report unusual vaginal bleeding, severe headache, chest pain, or one-sided leg swelling urgently. New symptoms are not proof that the medicine is unsafe, but they should be assessed before the next treatment decision.

Ask why letrozole is suitable for your tumour, how long the plan may continue, and whether you need a bone-density assessment. Clarify what to do after a missed tablet, which medicines may interact, and whether joint symptoms can be managed without stopping treatment.