What should you know about itchy palm and sole?

A single itchy palm and sole may follow repeated washing, sweating, friction, or contact with a product. Peeling or scale, especially around the toes, can occur with [Athlete's Foot](/conditions/athletes-foot/). Small fluid-filled blisters and later peeling can occur with [Dyshidrotic Eczema](/conditions/dyshidrotic-eczema/). Redness after a new soap, cleaner, glove, or shoe may suggest [Contact Dermatitis](/conditions/contact-dermatitis/).

Look at the border of the rash, the spaces between the toes, and whether the other hand or foot is involved. These details are more useful than the itch alone. The same symptom can have different causes, so avoid borrowing someone else’s treatment.

Wash with lukewarm water and a mild fragrance-free cleanser, then dry carefully. Apply a bland moisturiser to intact dry skin, wear breathable footwear, and change socks when damp. Keep nails short so scratching causes less damage. A clinician may recommend [Topical Antifungal Treatment](/treatments/medical-dermatology/topical-antifungal-therapy/) when examination supports a fungal infection.

Book an appointment when the itch persists, returns often, or causes fissures, blisters, or sleep disruption. Seek prompt care for rapidly expanding redness, pus, fever, severe swelling, or pain that limits hand use or walking.

Ask which diagnosis best matches the location and texture, whether a scraping or other test is needed, and how long to try the recommended treatment. Mention recent products, gym or pool exposure, sweating, allergies, and any household member with similar symptoms.