What should you know about intranasal exosomes?

Exosomes are tiny membrane-bound vesicles released by cells. They can carry proteins and other biological signals, which is why they are being explored in regenerative and aesthetic settings. Intranasal delivery places a spray or drops inside the nose, but the product is not interchangeable with a standard saline spray or an approved medicine. Source cells, purification, storage, sterility, concentration, and intended use can all vary.

Claims about brain, skin, immune, or anti-ageing effects should be treated cautiously unless a qualified clinician can explain the product and the evidence behind its specific formulation. A nasal route can also irritate the lining of the nose and may be unsuitable when there is active infection, bleeding, or recent nasal surgery.

Ask for the product name, source, formulation, storage requirements, and sterility controls. Confirm who is prescribing or administering it and whether the plan is part of an appropriately supervised clinical service. Tell the clinician about allergies, asthma, immune conditions, medicines that affect bleeding, pregnancy, and any nasal symptoms.

Do not share a nasal applicator or use a product that is unlabelled, expired, cloudy, damaged, or stored outside its instructions. More background on the material is available in [Exosomes](/materials/exosomes/).

Stop using the product and seek medical advice for persistent nose pain, swelling, repeated bleeding, worsening congestion, fever, or discharge. Get urgent help for trouble breathing, facial swelling, fainting, severe headache, confusion, weakness, or a sudden change in vision after use.

What exactly is in this formulation, and what is its intended medical purpose? How was it tested for sterility and handling? What side effects should prompt a call, and what safer established alternatives fit my goal?