What should you know about hyaluronic acid and hyaluronidase?

Short answer
Hyaluronic acid helps retain moisture, while hyaluronidase breaks down hyaluronic acid and should be used only for a clear clinical reason.
This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.
At a glance
- Hyaluronic acid
- Binds water and may support hydration or lubrication
- Hyaluronidase
- Enzyme that breaks down hyaluronic acid
- Safe next step
- Use only with clinician-directed advice
Why the distinction matters
Hyaluronic acid occurs naturally in the body and is also used in skin products and some injections. Its water-binding properties can support lubrication or surface hydration, depending on the formulation and location. Hyaluronidase is an enzyme that changes how quickly hyaluronic acid is broken down. It is not a moisturiser and is not a general antidote for every swelling. The right choice depends on why a product was used, where it was placed, and what a clinician finds on examination.
Before using either substance
Keep the product name, concentration, batch details, and date of use available for your clinician. Do not inject hyaluronidase or apply it to a problem area based on an internet suggestion. Tell the treating professional about allergies, medicines, previous procedures, and any infection or skin breakdown nearby. For a topical hyaluronic acid product, follow its label and discontinue it if irritation appears. A clinician should decide whether a change in appearance is expected swelling, an allergic response, infection, or another problem.
Warning signs
Get urgent medical help for severe or increasing pain, marked colour change, cold skin, new weakness, breathing difficulty, or swelling of the face or throat after a procedure. Seek prompt review for spreading redness, warmth, pus, fever, or symptoms that are worsening rather than settling. Do not wait for a home remedy to clarify a potentially serious reaction.
Questions to bring
Ask what the intended role of each substance is, what changes are expected after treatment, and which symptoms require same-day contact. Confirm who should assess you if swelling or pain increases and whether another ingredient could be responsible.
Find care
General Clinics & Polyclinics in Abu Dhabi
That answer is general. If you want it applied to your own case, these are licensed general clinics & polyclinics listed in Abu Dhabi.
27 Ar Ruwwad St - Shakhbout City - MSH4 - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, MetLife +20 more
Al Ruwais, Al Dhafrah
Accepts: Daman, Thiqa, AXA, Cigna +16 more
Al Bahyah - Al Bahyah Old - Abu Dhabi - United Arab Emirates
Accepts: Daman, Thiqa, Cigna, Allianz Care +18 more
Abu Dhabi
Accepts: Daman, Thiqa, AXA, Cigna +27 more
Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.
A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.
Questions people ask
Are hyaluronic acid and hyaluronidase the same?
No. They have opposing effects on hyaluronic acid and are used for different clinical purposes.
Can I use hyaluronidase at home?
Do not self-inject it or use it to manage unexplained swelling; obtain an assessment first.
Related
Related reading
Keep reading
Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.