Glioblastoma: what to know about the last 3 months

Changes vary between people. Headache, seizures, weakness, sleepiness, confusion, speech difficulty or reduced appetite may become more noticeable as the tumour and surrounding swelling affect brain function. Medicines may ease pain, nausea, seizures or swelling, while the care team reviews whether anticancer treatment still fits the person's goals and strength.

This stage can also involve conversations about comfort-focused care, home support, advance wishes and who should be contacted day or night. A family member can keep a simple record of symptoms and medicines. Learn more about glioblastoma on the condition page.

Ask the oncology team for a written plan covering medicines, mobility, meals, washing, communication and seizure first aid. Arrange help with transfers and avoid leaving someone alone if falls or confusion are concerns. A palliative care team can support comfort alongside cancer care; this does not mean care has stopped.

Discuss whether radiotherapy, brain tumour surgery, chemotherapy or a clinical trial could still help, and what burden each option may add. Decisions should reflect symptoms, scans, previous treatment and the person's wishes.

Contact the treating team promptly for a new seizure, repeated vomiting, rapidly worsening headache, a sudden change in alertness, new weakness, trouble speaking, or difficulty waking. During a seizure, protect the person from injury, place them on their side when safe, and do not put anything in their mouth. Use local emergency services for breathing problems, serious injury or a seizure that does not stop according to the team's instructions.

What changes should we expect, and whom do we call after hours? Which medicines should continue if swallowing becomes difficult? What support is available at home, and how will comfort be assessed?