What should you know about eflornithine for hirsutism?

Hirsutism means coarse, dark hair growth in a male-pattern distribution, such as the chin, upper lip, or chest, in a woman. Eflornithine acts locally on hair follicles and is usually applied to clean, dry skin as directed. Because it affects growth rather than the hair already above the skin, shaving, waxing, threading, or another removal method may still be needed while treatment is used.

Skin irritation, redness, stinging, dryness, or an acne-like reaction can occur. Avoid applying it to broken or irritated skin unless your prescriber gives specific instructions. Hirsutism can be linked with hormonal conditions, so cream alone may not explain or manage the cause.

Apply only the prescribed amount and wash your hands afterward. Keep it away from the eyes, lips, and inside of the nose. Tell the prescriber if you are pregnant, trying to conceive, breastfeeding, or using other facial products that irritate your skin. Discuss whether [Laser Hair Removal](/treatments/laser-and-energy/laser-hair-removal/) or [Electrolysis Hair Removal](/treatments/laser-and-energy/electrolysis-hair-removal/) suits your hair and skin type. If symptoms suggest a hormonal driver, a clinician may also discuss [Spironolactone Treatment](/treatments/medical-dermatology/spironolactone-therapy/).

Stop and seek medical advice for facial swelling, blistering, severe burning, or a widespread rash. Arrange assessment for rapidly increasing facial or body hair, deepening voice, new severe acne, scalp hair thinning, or menstrual changes, because these can signal a broader hormonal problem. Contact your prescriber if irritation does not settle after the instructed application changes.

Is my hair growth consistent with [Hirsutism](/conditions/hirsutism/), and should I be checked for a hormonal cause? How should I combine eflornithine with hair removal? Which facial products should I avoid? What reaction means I should stop?