Does multiple myeloma cause persistent bone pain?

Multiple myeloma affects plasma cells in the bone marrow. The disease can disturb the normal balance of bone renewal, making some bones weaker and causing a deep, aching pain. The back, ribs, hips, and other weight-bearing areas may be affected, and movement or pressure can make discomfort more noticeable.

Persistent bone pain also occurs with injuries, arthritis, infection, osteoporosis, and other conditions. A symptom does not establish a diagnosis. Assessment may include an examination, blood and urine tests, and imaging chosen according to your symptoms and medical history.

Book a medical appointment if pain lasts, returns, limits activity, or is not explained by an injury. Describe its location, character, timing, triggers, and effect on sleep or movement. Mention weight loss, unusual tiredness, repeated infections, numbness, or changes in bladder or bowel control.

Use only pain medicines that are suitable for you and follow the label or your clinician’s instructions. Avoid strenuous lifting or activities that sharply worsen pain until the cause and bone strength have been assessed.

Seek emergency care for sudden severe back pain with leg weakness, numbness around the groin, or loss of bladder or bowel control. Get urgent help after a minor injury if you cannot bear weight or suspect a fracture. Prompt assessment is also needed for severe pain with fever or rapidly worsening symptoms.

Ask which causes fit your pattern of pain, whether tests for bone or marrow problems are needed, and how to protect the painful area. Ask which pain relief options are safe with your other medicines and what changes should prompt urgent review.