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Does mastectomy treat Paget disease of the breast?

How the structures involved in Paget Disease of the Breast differ from normal
Illustration: How the structures involved in Paget Disease of the Breast differ from normal

Short answer

Mastectomy can treat Paget disease of the breast when disease involves the nipple area or deeper breast tissue extensively.

This answers one question. It is not a diagnosis and does not replace an assessment by a licensed doctor.

At a glance

Area affected
Nipple and areola skin, sometimes deeper breast tissue
Surgery options
Mastectomy or selected breast-conserving surgery
Planning factors
Disease extent and biopsy findings

Why the operation may be chosen

Paget disease affects the skin of the nipple and areola and can occur with DCIS or an invasive tumour elsewhere in the breast. Mastectomy removes the breast tissue and nipple-areola area, which may be recommended when the abnormal tissue is widespread, when a clear margin cannot be achieved with breast-conserving surgery, or when imaging or biopsy shows a deeper tumour.

For selected people whose disease is limited, surgery removing the nipple-areola complex and nearby tissue may be possible, often with radiotherapy. The decision depends on examination, mammography or other imaging, biopsy results, tumour extent, and personal priorities. Read more about [Paget Disease of the Breast](/conditions/paget-disease-of-the-breast/) and [Mastectomy](/treatments/surgical-oncology/mastectomy/).

Preparing for a decision

Ask the breast team whether the nipple skin change is isolated or connected to a tumour deeper in the breast. Discuss the planned margins, lymph-node assessment, reconstruction or flat closure, and whether radiotherapy or medicines may follow. If the proposed operation feels unclear, request a review of the imaging and pathology with the surgeon.

When to seek care

Arrange medical assessment for persistent nipple scaling, crusting, burning, bleeding, discharge, inversion, or a sore that does not heal. After treatment, report fever, wound redness, drainage, increasing pain, or new swelling promptly to the surgical team.

Questions for your doctor

Is there a deeper breast tumour as well as Paget disease? Could breast-conserving surgery be suitable? Will lymph nodes be checked? What reconstruction, radiotherapy, or medicine options should I consider?

Questions people ask

Does Paget disease always require mastectomy?

No. Some limited cases may be treated with surgery focused on the nipple area and nearby tissue, often with radiotherapy.

Why might lymph nodes be assessed?

Paget disease can occur alongside an invasive tumour, so the team may assess nearby nodes when the pathology or operation makes that relevant.

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Most UAE cancer care is delivered inside hospital services rather than by standalone oncology clinics, so these are licensed hospitals & medical centers listed in Abu Dhabi. Confirm the specific cancer service exists before you travel, and know that asking for a second opinion is routine.

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    Accepts: Daman, Thiqa, AXA, Cigna +30 more

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Second opinions are routine in cancer care and asking for one does not affect your treatment. How to arrange a second opinion in the UAE.

Ordered by verification status and how complete each clinic's public record is, then alphabetically. This is a directory listing, not a ranking — Zavis does not rate or recommend providers.

A factual listing drawn from the DHA, DOH and MOHAP licence registers. It is not a referral, an endorsement, or advice that any of these providers is right for you.

Medical disclaimer. This page is general health information, not medical advice, and it cannot diagnose you. Always consult a licensed healthcare provider about your own symptoms and treatment. In an emergency in the UAE, call 998 for an ambulance.