Anti-D immunoglobulin side effects: what to know

Some people notice discomfort where the injection entered the muscle, along with tiredness, headache, nausea, or a mild temperature. These effects are usually short-lived. Tell the clinician before treatment if you have had a reaction to immunoglobulin or any medicine, or if you have a known allergy. Your care team can explain which symptoms fit the product used and your medical history.

A side effect is different from a symptom caused by the pregnancy or the event that led to treatment. Bleeding, abdominal pain, faintness, and reduced fetal movement should be assessed on their own rather than attributed to the injection.

Rest if you feel unwell, drink fluids if you can, and follow the medicine advice given by your maternity team. Check before taking an over-the-counter product during pregnancy. Note when a symptom began, how it changes, and whether it is local or affects your whole body. Contact the service that gave the injection if symptoms are persistent, worsening, or difficult to manage.

Call emergency services for difficulty breathing, wheezing, swelling of the face, lips, tongue, or throat, widespread hives, severe dizziness, or collapse. Contact your maternity unit urgently for heavy bleeding, severe or one-sided pain, fever, fainting, or reduced fetal movement. These warning signs require assessment even if they began after the injection.

Ask which effects are expected with your injection, how to manage soreness or headache, which pain medicines are suitable for you, and what number to use after hours. Ask whether a future dose or antibody test needs a note about this reaction.